What are the top 8 best smart pill or nootropic supplements to buy and why? Well that is why we are here today and to give you a better idea of the pros and cons.

First of all, Lets have the Wikipedia definition put in for what is a nootropic or a brain Fog supplement or supplement:

“Nootropics (/noʊ.əˈtrɒpɪks/ noh-ə-TROP-iks) (colloquialsmart drugs and cognitive enhancers) are drugssupplements, and other substances that may improve cognitive function, particularly executive functions, memory, creativity, or motivation, in healthy individuals.[1] “See Wikipedia.com

The art of alchemy may be dead but the search for the philosopher’s stone is not. It’s simply transfigured into the art of nootropic stacking, which simply refers to: Combining two or more cognitive enhancing or neuroprotecting substances at the same time to produce a sum greater than its parts.

With all that said, The one that comes out the best for me is which I’ll get to first and then follow with the others is :

Qualia Mind

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So Qualia has shown to be consistently the best over a long period of time and has been in the market for a while now and built up a good name.
Here below are just some of the numerous reviews from people:

 “best natural product”

“I have tried many different nootropics over the years and I can honestly say Qualia is on a whole different level. I have experienced profound increases in cognition, focus, motivation and overall sense of well being. The effects last for much of the day and fortunately do not interfere with sleep, if anything it seems to aid in getting to sleep quicker”

“Ive been taking qualia for a couple weeks now and my memory has improved also while im at work and studying im making connections that I never have before.and lastly my anxiety has been almost non existant,which im very pleased with.Overall I think this product is great!”

Their website and many reviews people have done online shows why it is such an incredible brand. So much so that they have grown to be the top brands across the globe. So they are obviously producing many satisfied customers. In a short time, Qualia mind has secured a place as one of the most highly-rated brain supplements on the market.

Qualia Mind is a fast-acting nootropic designed to improve brain performance.

More specifically, Qualia Mind has the following key strengths:

  • Lift brain fog
  • Boost concentration and focus
  • Increase energy levels
  • Increase “brain nutrition”
  • Promote mental clarity
  • Benefits of Qualia Mind’s nootropic stack include:
  • Enhanced clarity, focus, and fluidity (without crashing)
  • Increased empathy and alertness
  • Heightened willpower
  • Decreased procrastination
  • Effects last up to 6 hours with a single dose.

Clearly Qualia Mind is a nootropic focused on improving immediate, short-term executive mental functions.

Developed by the Neurohacker CollectiveQualia Mind has seen several iterations. Qualia features nootropics like caffeine, L-theanine, and 21 other powerhouse substances.

Some cons:

Your level of sensitivity will determine how you perceive the effects. I notice a slight buzzing sensation toward my prefrontal cortex. This buzzing sensation is similar to what you might experience on caffeine but without any jitters. Plus, this sensation coincides with a marked clear-headedness that enables prolonged focus.

If you notice that you tend to get distracted easily or lose focus on an important task, Qualia Mind can help you zoom in and get things done!

Now onto some of the other great and top 8 Brain Fog smart pill Enhancers or supplements

Review 2 – Alpha Brain

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Alpha Brain

Produced by ONNIT’s Lab since 2010, Alpha Brain is definitely one of the top nootropic stacks available.

Alpha Brain’s Strengths and Key Features

  • Alpha Brain’s nootropic stack benefits include:
  • Supports synaptic plasticity
  • Enhances your mood and reduces social anxiety
  • Stimulates nerve growth for better brain development
  • Loss of concentration and mental abilities due to normal aging can indeed be reversed.
  • Boosts energy, alertness and memory.
  • Improves mental speed, in response to stimuli.


  • I just did not feel the effects like I have with Qualia mind and some of the others

3rd Review – CILTEP

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CILTEP is an acronym for chemically-induced long-term potentiation. Developed by Natural Stacks, it’s widely used and is currently among the best nootropic stacks. This nootropic stack aims to heighten your level of concentration, focus, and memory function.

CILTEP’s Strengths and Key Features

  • The key feature of CILTEP is its ability to stimulate the brain to enhance your hippocampus (associated with memory). CILTEP is designed to induce long-term potentiation (LTP) in the brain, which is crucial to developing and stabilizing of new memory.
  • Another key feature is CILTEP’S ability to strengthen neural synapses, allowing signals to move faster across synapses. Faster connections provide a tremendous boost to your coordination and mental functions.


While being a great Nootropic and one which I felt did a fantastic Job, I just think the Qualia mind just beats this in terms of the efficacy of Qualia

4th for review – Mind Lab Pro

Mind Lab Pro® Universal Nootropic™

Mind Lab Pro® nootropic stacks-within-stacks strategy layers the brain benefits for an all natural, all powerful Universal Nootropic™ design.

Mind Lab Pro® packs its all natural capsules to their edges with nootropic stacks within stacks within stacks, achieving a unique and smartly crafted synergy of brain boosting benefits. And while each nootropic stack focuses on a particular cognitive issue, the sum total of this nootropic synergy comes out to the same thing: 100% Brainpower™.

Review 5 – STAQ Performer

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STAQ Performer

STAQ Performer is certainly one of the top nootropic supplement on the market. 

RECOMMENDED TO: Anyone who is looking for optimal brain performance and great short- and long-term results without overspending on a supplement

STAQ Performer contains some of the most researched, well-dosed, and high-quality nootropics on the market. Our experience shows that it delivers outstanding short-term effects, such as improved focus, energy, attention, and optimal brain performance.

It is also one of the safest supplements for long-term use. Due to a moderate pricing and great user experience, it scored to very high on my Nootropics Ranking List. 


  • 12 scientifically researched ingredients
  • Short-term effects are fantastic
  • Expect lots of energy, focus, motivation, creativity, and overall well-being
  • It’s a premium product for a reasonble price


  • Running out of stock

Review 6 – Performance Lab® Energy

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I used Performance Lab® Mind for around 1 month and which I found to be a very good Supplement for Nootropics and certainly is one of the top ones

  • Pros

Performance Lab® Mind enhances performance-driven cognitive functions: Focus, speed, energy, memory, motivation and more.

Mind is also the first nootropic to help you bounce back faster by fighting stress burnout – all while supporting brain health over time.

Mind features Cognizin® (boosts brain energy 13.6%) and eco-friendly Sharp-PS® Green, plus the highest-potency Maritime Pine Bark Extract (95% proanthocyanidins) on the market.


  • I did look at some of the reviews and while there are a stack of great reviews , there were some that said they had not felt the effects as yet after 2 weeks. I certainly felt more awake and focused with them though

Review 7 – Awaken

Awaken by Awakened Alchemy is the go-to supplement for any biohacking transhumanists out there. This nootropic stack doesn’t leave anything to chance as it seeks to meet the needs of the natural, organic and health-conscious types.

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  • A closer look at its list of ingredients reveals the like of l-theanine, PQQ, n-acetyl l-tyrosine, and CDP choline are some of the ingredients that comprise its diverse list of ingredients.One thing that drew our attention to this product is that it is designed to be immediate-acting.

Therefore, if you’re looking to make some quick wins this might be the best product for you.


  1. On the flipside, though, products that bring some near-instant results also tend to build a tolerance over time. And that might be the case with Awaken. So it’s probably best to include a few off-cycle sessions in the course of using it to attain long-term efficacy.

Review 8 – Noocube



  • Described as a synergistic blend that can help support mental speed, memory, and focus, Noocube seems like a nootropic cut from a different cloth. To begin with, it is claimed to boost brain power effectively giving the user an IQ jump of 50 points.
  • Keeping that in mind, NooCube may seem like one of the brightest and best-made stacks in this game. But is there more than meets the eye? Well, this smart formula is almost perfect except for the fact that it’s offered in some pretty small doses.
  • On a scale of 10, NooCube fetches an incredible 7.5/10. That’s to say that it’s good enough though.
  • Considering its list of ingredients and approach, it’s possible to see that the product heavily relies on a choline-based strategy. Some of its key ingredients include Huperzia, Bacopa, and Alpha-GPC which are known for stimulating the mind without the jitters typical of caffeine.


  • Another one of those with a possible build up of tolerance over period of time
  • It’s recommended to take 2 capsules with breakfast. However, those with higher tolerance should consider increasing their dosage to 3 or 4 capsules per day. Care should be taken not to exceed 4 capsules a day.

Further Insights and information for those wanting to know more about the smart pills and nootropics supplements Industry

As you may or may not know, Nootropic stacks come in many different shapes, colors, forms, and dosages. So with this, how does one know what is the best nootropic to then choose and how do you go about determining which one to buy?

Unfortunately, for many people this is the problem. As someone who is looking for a viable way to improve their mental health, or trying to clear their brain fog, finding the best nootropics or smart drugs often proves to be a tough call due to the wide variety of the products involved.

Smart pills was coined by Romanian scientist Corneliu E. Giurgea in 1972 when he created a drug he believed enhanced memory and learning. (Silicon Valley types often cite his tagline: “Man will not wait passively for millions of years before evolution offers him a better brain.”) But today it’s an umbrella term that includes everything from prescription drugs, to dietary supplements on sliding scales of safety and effectiveness, to commonplace stimulants like caffeine — anything a person might use in an effort to enhance cognitive function, whatever that might mean to them. Obviously, not everyone wants to take a risky sleep medication.

Standalone nootropics produce standalone effects. Stacking nootropics may synergize, multiply, and complement standalone effects for transcendent cognitive enhancement.

There are so many things that can go wrong with the human brain. And a group of neurohackers will offer a variety of opinions on the best solution for each thing.

But take a step back and you notice something. People generally sort their brain hacking goals into a few well-defined categories. Then look for the best nootropic to address each one.

Another thing we learn quickly is that there is no ‘one-pill’ solution to cognitive optimization. It often takes a ‘stack’ of several supplements to get to where we want to go.

Some ideas of what is the Nootropic best for and the recommended Nootropics for that specific area you would like to zone in on or that might be what you are needing or looking for:

What is the Nootropic best forRecommended Nootropics
Processing speed, Decision-Making, Focus, Flow, & ThinkingAcetyl-L-Carnitine (ALCAR), Aniracetam, Caffeine, CDP-Choline, Lion’s Mane Mushroom, NALT, B-Complex
Learning & MemoryAcetyl-L-Carnitine (ALCAR), Aniracetam, Caffeine, CDP-Choline, Lion’s Mane Mushroom, NALT, B-Complex
Anxiety & DepressionAniracetam, CDP-Choline, Bacopa Monnieri, L-Theanine, Rhodiola Rosea, Sulbutiamine, B-Complex
Energy & MotivationAcetyl-L-Carnitine (ALCAR), Alpha Lipoic Acid, Caffeine, CDP-Choline, Rhodiola, CoQ10, PQQ
Brain Repair & MaintenanceAcetyl-L-Carnitine (ALCAR), Aniracetam, Caffeine, CDP-Choline, DHA, Phosphatidylserine (PS), Vinpocetine, Rhodiola Rosea, Pine Bark Extract

What are the ingredients in Nootropics?

So what does it contain such that it can do all this for you? Here are the ingredients breakdown for those analytical people:

Acetyl-L-Carnitine HCL

ALCAR is often used as a sports supplement because of its positive effect on energy metabolism.

Artichoke leaf extract

A specific artichoke extract (Luteolin) is known to inhibit PDE4; an enzyme which breaks down cAMP in the brain. Inhibiting PDE4 will increase brain cell signalling.

Bacopa monnieri extract

Bacopa Monnieri (Indian Pennywort) is easily one of the best Qualia Mind ingredients and a major selling point of this nootropic. Daily Bacopa monnieri supplementation improves memory function. It is especially good for older people, or those struggling with memory problems. The extract used in Qualia Mind is potent.

Rhodiola rosea extract

Rhodiola Rosea is an excellent anxiolytic and as such consuming Rhodiola Rosea reduces anxiety and improves cognitive performance while under stress. The 300mg in Qualia Mind is enough to make you calm and clear-headed when you need to be most.


Phenylalanine is an amino acid. Acts as a building block for protein.

Uridine-5-Monophosphate heptahydrate disodium

Uridine Monophosphate is one of the most exciting nootropics in the world right now. The studies have shown to be very promising. Uridine has been found to improve learning, and to accelerate synaptic formation


Tyrosine is a powerful amino acid. Multiple clinical trials have shown that Tyrosine supplementation improves cognitive performance in people placed under extreme stress – cold exposure, sleep deprivation, and more. With Qualia Mind there is more than enough for you to see all the benefits associated with Tyrosine.

Taurine – 200mg

Taurine is another amino acid in Qualia mind that is sometimes supplemented for its general health-promoting properties and for it’s cardiovascular boost for health.

L-Theanine – 200mg

Theanine is another amino acid. Theanine can be a great nootropic; it reduces the side effects of caffeine while heightening its focus-boosting effects.

Alpha-GPC – 200mg

Alpha-GPC increases acetylcholine levels in the brain. Acetylcholine is primary executive neurotransmitter in humans. More acetylcholine means faster information processing, faster memory recall, and faster reaction times. Alpha-GPC is a superb focus and memory booster. So this is one of the main ingredients within Qualia that really gives it’s the edge.

Citicoline – 150mg

Citicoline is the go-to nootropic for improving focus, learning and recall speed. Like Alpha-GPC, it increases acetylcholine levels in the brain, which increases concentration, information processing, and more. Citicoline also promotes healthy brain cell formation.

Coffeeberry WCFE – 129mg

Whole Coffee Fruit Extract is reported to dramatically increases BDNF levels. It is also said that WCFE protects brain cells from oxidative damage.

Mucuna pruriens – 100mg

Mucuna pruriens is usually used in hormone supplement and it raises testosterone production. These claims seem to be soundly proven by clinical studies. So having higher testosterone levels improves mood and cognitive performance.  


Phosphatidylserine is a necessary component of brain cell membranes. it is also needed for cell signalling – without enough phosphatidylserine, your brain can’t get rid of dying brain cells! So this is another one of the top ingredients in Qualia Mind.

As humans, our body does produce it s own phosphatidylserine, but as we get older, our levels steadily decline. Supplementing with phosphatidylserine has been shown to significantly improve several different aspects of cognitive function, particularly in older groups


Theobromine is a compound found in cocoa. Theobromine is a caffeine alternative.


DHA is the fatty acid which makes up a staggeringly large proportion of your brain’s gray matter. Consuming DHA is a fantastic way to promote a healthy, functioning brain and to reduce your risk of experiencing cognitive decline.

Celastrus paniculatus seed extract

Celastrus paniculatus is a tree native to India and has been shown to enhance cognitive function by improving memory and learning, and to protect the brain from oxidative damage and neurotoxicity. Anxiolytic, antidepressant, analgesic and anti-inflammatory effects have also been described.

Ginkgo biloba leaf extract

Of all the Qualia Mind ingredients, Ginkgo biloba is probably the one that older people will be most interested in. Gingko biloba improves cerebral blood flow. It does this by increasing blood viscosity and dilating your blood vessels. This leads to better oxygenated brain cells, which means better mental performance.

Coleus forskohlii root extract – 20mg

Coleus forskohlii – or its active ingredient Forskolin – is a common ingredient in testosterone boosters. Thus again with a testosterone booster, it improves mood and cognitive abilities.


PQQ – or Pyrroloquinoline quinone acts as an anti-oxidant and then be recycled back into an active form by glutathione. PQQ has been found to reduce biomarkers of inflammation by as much as 45%.

Huperzina serrata leaf extract (1% Huperzine A)

Huperzine A inhibits the enzyme acetylcoloinesterase. This enzyme breaks down acetylcholine between synapses. By inhibiting acetylcholinesterase, Huperzine A causes a steady build-up of acetylcholine, which improves multiple different measures of mental performance.

The best Nootropic Smart pill supplements for your health

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